Myocardial Injury in Burn Shock

Burn injury in Mottahari Burn Center in Tehran, Iran

Cytosolic heat shock protein 60, apoptosis, and myocardial injury.

BACKGROUND Heat shock proteins (HSPs) are well known for their ability to "protect" the structure and function of native macromolecules, particularly as they traffic across membranes. Considering the role of key mitochondrial proteins in apoptosis and the known antiapoptotic effects of HSP27 and HSP72, we postulated that HSP60, primarily a mitochondrial protein, also exerts an antiapoptotic eff...

Liver Disease in Burn Injury

OBJECTIVE To assess mortality risk and extent of increased length of hospital stay in patients with burn injury with preexisting liver disease. METHODS Records of 31,338 adults who were admitted with burns to 70 burn centers were reviewed from the American Burn Association National Burn Repository. Demographics, percentage burn, and medical characteristics of 180 patients with liver disease w...

Burn injury in Mottahari Burn Center in Tehran, Iran

DEAR EDITOR Burn is one of the devastating conditions in emergency medicine resulting into physical and psychological disabilities.1 During pregnancy, it has an increasing trend for mortality and morbidity of both mother and infant.2 So practical activities to decrease its physical and emotional complications seem mandatory.2 For survivors, the most persisting problem is scarring while healing ...

American Burn Association practice guidelines burn shock resuscitation.

Guidelines • Adults and children with burns greater than 20% TBSA should undergo formal fluid resuscitation using estimates based on body size and surface area burned. • Common formulas used to initiate of resuscitation estimate a crystalloid need for 2 to 4 ml/kg body weight/%TBSA during the first 24 hours. • Fluid resuscitation, regardless of solution type or estimated need, should be titrate...